Terumo has decided to acquire Aortica corporation, which is a US-based company dedicated to advancing the science of personalised vascular therapy. Aortica has developed an automated case planning software known as “AortaFit”, which is designed to precisely match fenestrations on an endograft with the unique locations of each individual patient’s branch arteries during fenestrated endovascular aortic repair (FEVAR).
A press release reports that the AortaFit technology is intended to improve graft anchoring while minimising the potential for endoleaks and migration that can result from the endovascular treatment of complex abdominal aortic aneurysms. Aortica has reported successful results for the first 30 patients undergoing FEVAR planned and performed using AortaFit as part of an FDA approved physician-sponsored investigational device exemption (IDE) study (led by Benjamin Starnes, University of Washington, USA). In the study, 100% of patients who had grafts planned by the automated software were successful including 16/30 treated with the TREO stent graft from Terumo Aortic.
Starnes comments: “Although several endografts are being studied under our protocol, the TREO abdominal aortic endograft has become our platform of choice because of its deliverability, conformability and graft design conducive to creating fenestrations. TREO is most likely to allow strut-free fenestrations in our series.”
According to the press release, Aortica also has the BoulEVARd covered stent graft that has built specifically for FEVAR. The balloon expandable device has been designed to enable reliable engagement into the main body graft while improving conformability to the native artery.
Paul Holbrook, president of Terumo Aortic, says: “This acquisition is a tremendous opportunity for Terumo Aortic to expedite the development of a first-in-class, purpose-built FEVAR system, particularly in the USA. By leveraging the unique AortaFit system and BoulEVARd covered stent graft together with the proven capabilities of TREO, we aim to transform vascular disease management in this challenging patient population. Furthermore, we are convinced that the system helps us contribute to personalised therapy.”
Terumo, the press release says, will advance the development of the Aortica’s products, and then launch them in the USA, Europe, Japan and other areas. The transaction is aimed to close within 2019 and will be funded through cash on hand. Terumo does not regard the impact of the acquisition on Terumo’s business performance of the fiscal year ending 31 March 2020 as significant.